Amoxycillin 500mg + Clavulanic Acid 125
Generic name:
Amoxicillin/clavulanic acid – oral
Pronunciation
(a-MOX-i-SIL-in/KLAV-ue-LAN-ik AS-id)
Brand name(s)
Wismox-CV 625
Prescription status:
Prescription required
Marketed by :
Bioiwis Pharmaceuticals
Drug classification:
Antibiotic combinations
What is this used for:
- Lower Respiratory Tract Infections
- Otitis Media
- Sinusitis
- Skin and Skin Structure Infections
- Urinary Tract Infections
When to not take this medicine:
- Hypersensitivity/Known Allergy to this medicine combination
- Liver disease
- Kidney disease
- Metabolic acidosis
How should I take the medicine?
Take this medicine with an adequate amount of water as directed by the physician. Do not take
this medicine in small or larger amounts than recommended.
How this medicine works:
Amoxicillin helps in killing bacterial cells by preventing the growth and development of bacterial cell walls. Clavulanic acid helps in the inactivation of enzyme synthesis that is important for bacterial growth.
Side effects
- Nausea(Less common)
- Vomiting(Less common)
- Diarrhea(Less common)
- Dizziness(Less common)
- Irregular heartbeat(Less common)
- seizures(Less common)
- Rashes(Less common)
- Sore throat(Less common)
- Headache(Less common)
- Dark urine(Less common)
- Loss of appetite(Less common)
Pregnancy warning: Not Assigned (Unknown)
Use of this medicine is not recommended for individuals who are pregnant or planning to become pregnant unless absolutely necessary as the safety and efficacy of this medicine is not well established. Inform your doctor about the use of either medicines. All the risks and benefits should be discussed with the doctor before taking this medicine.
Lactation warning:
Use of this medicine is not recommended for lactating and breastfeeding mothers unless absolutely necessary. Inform your doctor about the use of this medicine. All the risks and benefits should be discussed with the doctor before taking this medicine.
Renal dose adjustments:
Care must be taken for individuals with kidney disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative on the basis of creatinine clearance values.
Hepatic dose adjustments:
Care must be taken for individuals with liver disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative.
Drug interactions:
- Methotrexate -major
The use of this medicine with methotrexate may result in the increase in the serum levels and effects of methotrexate. This may cause serious side effects like mouth ulcers, vomiting, lowering of blood cell counts etc. Inform your doctor if you experience any unusual signs and symptoms and your doctor may consider either the dose adjustment or any alternative medicine based on your condition and the therapeutic response with the medicine.
- Warfarin- Moderate
The use of this medicine with warfarin may result in the increase in the risk of bleeding especially in old or elderly patients who are already known to have liver or kidney impairment. Inform your doctor if you experience any unusual signs and symptoms like blood in urine, stools, headache, weakness etc, your doctor may consider either the dose adjustment or any alternative medicine based on your condition and the therapeutic response with the medicine.
- Tetracycline- Moderate
The use of this medicine with tetracycline may result in a decrease in the effectiveness of this medicine. Your doctor may consider any alternative medicine based on your condition and the therapeutic response with the medicine.
- Doxycycline- Moderate
The use of this medicine with doxycycline may result in a decrease in the effectiveness of this medicine. Your doctor may consider any alternative medicine based on your condition and the therapeutic response with the medicine.
Alcohol interactions:
Consumption of alcohol is not recommended while taking this medicine as it may cause interactions and lead to serious adverse effects and may worsen the health condition.
Food interactions:
N/A
Expert Advice:
- The use of this medicine is not recommended for individuals diagnosed with chronic alcoholism.
- The use of this medicine is not recommended for individuals with kidney or liver diseases as this may cause organ failure or may cause severe health complications like coma or even death.
- Discuss with the doctor about the risk associated with this medicine if taken during pregnancy or breastfeeding.
Missed dose instructions:
Take this medicine as soon as you remember. However, if it is almost the for your next dose skip the dose and go back to your regular dosing schedule. Do not double dose to make up for the missed dose.
Overdose Instructions:
Seek emergency treatment or contact your physician in case if you experience any unusual signs and symptoms during the treatment with this medicine.
Storage Instructions:
Store the medicine in a cool and dry place. Keep the medicine away from the reach of the children
References:
1. AMOXICILLIN AND CLAVULANATE POTASSIUM TABLETS USP, 500 mg/125 mg and 875 mg/125 mg22742275Rx only [Internet]. Dailymed.nlm.nih.gov. 2021 [cited 5 February 2021]. Available from: https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=22b16383-9ce3-45e7-80c3-db332f59abbf&type=display